… We found that CSF obtained from Alzheimer's disease (AD) and DLB patients enhanced the
αS fibril formation compared with tauopathy and … Alpha-synuclein and Parkinson's disease …

… atrophy (MSA) and Lewy body diseases including Parkinson's disease (PD) and dementia
with Lewy bodies (DLB) (α-synucleinopathies). To test the hypothesis that patients with α-…

… in vivo. We hypothesized that exosomal α-synuclein species from … cerebrospinal fluid
from patients with Parkinson’s disease, … dysfunction increases exosome-mediated alpha-synuclein …

… Alzheimer disease (AD) is the most common form of … to increase worldwide, causing suffering
for the patients and their … forms of α-synuclein are neurotoxic in vitro and in vivo[20–23]. We …

… Ultimately, high molecular weight cytosolic fractions enhances … of Lewy body (LB)-associated
αSyn. This study provides evidence from human samples to support previous in vitro and …

… of amplified fibrils to those assembled in vitro by incubation of … TEM images indicates an
increase in fibril diameter with a … cerebrospinal fluid as starting material, have produced Asyn …

… fibril-templating activity in tissues and cerebrospinal fluid (CSF). … At day-in-vitro (DIV) 7,
ssFibrils were added to each well of … across different fibril concentrations to enhance sensitivity. …

… and form the typical intracellular Lewy bodies. Intriguingly, the … To validate the in vitro seeding
capacity of the fibrils, we … 1 μg/μl human alpha synuclein (α-syn) pre-formed fibrils (PFF) or …

… Cerebrospinal fluid of Alzheimer's disease and dementia with … in vitro … Lewy body
variant of Alzheimer's disease: alpha-synuclein in dystrophic neuritis of A beta plaques …

… was found to enhance the aggregation rate of α-synuclein in vitro. Moreover… protein found
in plasma and cerebrospinal fluid, which is believed to be a … Alpha-synuclein in Lewy bodies …